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ORIGINAL ARTICLE
Year : 2018  |  Volume : 4  |  Issue : 2  |  Page : 24-28

Childhood And Adolescence Ovarian Malignancy : A Study in A Tertiary Care Centre in Bihar


1 Additional Professor, Dept. of Pathology, IGIMS, Patna, India
2 Senior Resident, Dept. of Pediatrics, IGIMS, Patna, India
3 Additional Professor, Dept. of Gynecological Oncology, IGIMS, Patna, India
4 Senior Resident, Dept. of Gynecological Oncology, IGIMS, Patna, India
5 Professor Anesthesiology, IGIMS, Patna, India

Correspondence Address:
Jaya Kumari
Additional Professor, Dept. of Gynecological Oncology, IGIMS, Patna, Bihar
India
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Source of Support: None, Conflict of Interest: None


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Background: Ovarian tumour in children and adolescent girls is uncommon but important part of gynaecological malignancies. They account for 1% of all the childhood malignancies and 8% of all abdominal tumours in children. Incidence is reported to be 2.6 cases per 100,000 girls per year and almost 10-30% of all the ovarian neoplasms occurring in girls up to 17 years of age are malignant We share our experience in childhood ovarian cancers, analysing a series of cases with respect to the clinical profile, treatment and survival. Methods: All newly diagnosed ovarian tumours in children up to 20 years of, registered in Gynaecological Oncology of Indira Gandhi institute of medical science between 2014 and 2017 were retrospectively reviewed. Observations: There were 12 patients with newly diagnosed ovarian malignancies. The mean age at presentation was 14 ± 4 years. The most common symptoms at presentation were acute abdominal pain (48.9%) and abdominal mass (40.4%). Histology was germ cell tumours in 11 cases and nongerm cell tumours in one cases. Out of 11 GCTs, 10 patients underwent fertility sparing surgery and one patient lost after neoadjuvant chemotherapy. One patient of mucinous adenocarcinoma underwent debulking surgery. Six patients lost to follow up after surgery and three had taken post-surgery chemotherapy. At a median follow up of 15 month, the 3 year disease?free survival was 46. 62 ± 2.3 % and 3 year overall survival (OS) was 38 ± 3.46 %. Conclusion: Germ cell tumours are the most common ovarian malignancy in children. With surgery and chemotherapy using BEP, good outcome can be expected in these patients.


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