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Year : 2020  |  Volume : 6  |  Issue : 1  |  Page : 13-17

“A comparative evaluation of intraarticular bupivacaine and neostigmine with bupivacaine and fentanyl for post operative analgesia in arthroscopic knee surgeries: A prospective randomized study”

1 Assistant Professor, Dept. of Trauma and Emergency (Anesthesiology), IGIMS, Patna, India
2 Associate Professor, Dept. of Anesthesiology, Super Specialty Cancer Institute & Hospital, Lucknow, India
3 Professor, Dept. of Anesthesiology, ELMC& H, Lucknow, India

Correspondence Address:
Mohd Asim Rasheed
Associate Professor, Super Specialty Cancer Institute & Hospital, Lucknow
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Source of Support: None, Conflict of Interest: None

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Context : Now a days arthroscopic surgeries are very commonly performed and are associated with post-op pain. Various method of relieving pain is present like NSAIDS, Opiods, peripheral nerve blocks and local anaesthetics. In this study we are trying to search a novel method to control post operative pain . The present study aims to compare the effects of intraarticularly instilled Bupivacaine and Neostigmine with Bupivacaine and Fentanyl for pain relief following knee arthroscopic surgery. Aims and objective : To compare the efficacy of bupivacaine and Fentanyl with bupivacaine and Neostigmine administered intraarticularly for postoperative pain relief in patients undergoing knee arthroscopic surgeries and comparing duration of analgesia, hemodynamic parameter and side effects if any. Material and Method- It is a prospective randomized study. Sample size was 75 divided in three groups. ◼ GROUP P - Intraarticular injection 19ml of 0.25% bupivacaine as control group + 1 ml NS ◼ GROUP N- Intraarticular injection of 19 ml of 0.25% bupivacaine + 1 ml (500 mcg ) of neostigmine. ◼ GROUP F- Intraarticular injection of 20ml of 0.25% bupivacaine + 1 ml (50 mcg )of fentanyl. Result : Demographic variable amongst all three groups were matched. In this study mean duration of analgesia time in group P is significantly lower than group N and Group F (p value < .05)however duration of analgesia time in Group N and Group F are comparable but Group N showed slightly higher duration of Analgesia. Conclusion : Thus, we found that addition of neostigmine or fentanyl to bupivacaine increases the duration of analgesia in the post-operative period.

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