| ORIGINAL ARTICLE |
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| Year : 2020 | Volume
: 6
| Issue : 1 | Page : 18-20 |
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Evaluation of serum prolactin, FSH and LH in infertile females with thyroid disorders
Vibha Sushilendu1, Kalpana Singh2, Uday Kumar3, Rekha Kumari4
1 Senior Resident, Dept. of Biochemistry, IGIMS, India
2 Associate Professor, Dept. of Reproductive Medicine, IGIMS, India
3 Professor, Dept. of Biochemistry, PMCH, India
4 Additional Professor & Head, Dept. of Biochemistry, IGIMS, India
Correspondence Address:
Kalpana Singh
Associate Prof. & Head Reproductive Medicine, IGIMS, Patna
India
 Source of Support: None, Conflict of Interest: None
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Background: Infertility represents a common condition, with important medical, economic and psychological implications. Thyroid dysfunction interferes with human reproductive physiology. It reduces the likelihood of pregnancy and adversely affects pregnancy outcome, thus becoming relevant in the algorithm of reproductive dysfunction.
Aims and objectives: To estimate serum prolactin, FSH and LH in hypo, hyper and euthyroid female subjects and find their association with thyroid status.
Material methods: a cross-sectional observational study was done . 100 infertile females of age group 20-40 years, who were then subdivided into euthyroid, hypothyroid and hyperthyroid cases Serum Prolactin, FSH, LH,TSH,TotT3,TotT4 were estimated by Chemi-luminescence immunoassay method
Results: The infertile women with hypothyroidism had significantly higher prolactin levels than the other groups
Conclusion: TSH has a positive correlation with serum Prolactin level.Assessment of serum TSH and prolactin levels should be made mandatory in the work up of all infertile women, especially those presenting with menstrual irregularities
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