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Year : 2020  |  Volume : 6  |  Issue : 1  |  Page : 21-25

Retrospective analysis of clinico-pathological characteristics of ovarian cancer and audit of cytoreductive surgery done at tertiary care center in Eastern India

1 Ex-Senior Resident, Gynecological Oncology, IGIMS, India
2 Professor & Head, Hematology, IGIMS, India
3 Professor & Head, Gynecological Oncology, IGIMS, India
4 Assistant Professor, IGIMS, India
5 Senior Resident, Gynecological Oncology, IGIMS, India

Correspondence Address:
Sangeeta Pankaj
Prof. & Head Gynecological Oncology, SCI, IGIMS, Patna
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Source of Support: None, Conflict of Interest: None

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Ovarian malignancy is a common and highly morbid cancer of females. Advanced stage ovarian cancer warrants extensive surgery to achieve the goal of optimal cytoreduction i.e. no residual macroscopic disease, which is an independent prognostic factor contributing to survival of these patients population. The aim of index study is to describe the incidence, pattern and management of ovarian cancer at a tertiary care center in eastern India and also audit the surgeon’s performance in treating these patients surgically and the improvements if any, over a period of 7 years. No such studies focusing on analysis of pattern of ovarian cancer presentation and the optimal surgery rates alongwith outcomes have yet been published from this region. Method: A retrospective analysis of all operated cases of histologically proven ovarian cancer at our institute from December 2009 to March 2016 was carried out. Results: Ovarian cancer was the predominant cohort undergoing surgery for gynecological malignancies. The most common variant was epithelial ovarian cancer and 30 to 50 years was the commonest age group afflicted. The rate of surgery has been increasing consistently over the years and the rate of achieving optimal cytoreduction has improved significantly. The operability was better in the patients receiving neoadjuvant chemotherapy but the primary surgery arm has also seen improvement in achieving optimal cytoreduction. The probability of achieving R Zero has improved from 0.5 in 2009 to 0.95 in 2016. Conclusion: The operative outcome and quality of life of patients has shown considerable improvement in hand of surgeon dealing with such cases at a high volume tertiary care center. This emphasizes upon the significance and need for well equipped, sophisticated, multi-disciplinary tertiary care center catering to population with a high propensity and prevalence of Gynaecological malignancies.

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