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ORIGINAL ARTICLE
Year : 2021  |  Volume : 7  |  Issue : 1  |  Page : 28-34

Study of seroconversion for severe acute respiratory syndrome: Coronavirus 2 IgG antibody in health-care workers in a non-COVID tertiary care hospital


Department of Biochemistry, IGIMS, Patna, Bihar, India

Correspondence Address:
Rekha Kumari
Department of Biochemistry, IGIMS, Patna, Bihar
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jigims.jigims_3_21

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Background: SARS-CoV-2 possess higher risk of infection to Health Care Worker (HCW) from patients or other fellow HCW. Aims and Objective: The aim of this study is to estimate the seroprevalence of SARS-CoV-2 Ig G antibody in a sample of HCW chosen randomly from a tertiary care hospital in Patna Bihar. Results: Of the 169 participants screened from 8 July to 26 August 2020, 10.1%, (95% CI: 5.97-15.62) were seropositive for IgG antibody against SARS-CoV-2. The cumulative prevalence of SARS-CoV-2 infection (presence of antibodies or past or current positive rRT-PCR) was 10.7% ( 95% CI: 6.4–16.3). Among those with evidence of past or current infection, 5.6 % (1/18) had not been previously diagnosed with COVID-19. Conclusion: We have observed a relatively low seroprevalence of antibodies among HCW at the peak of the COVID-19 epidemic in IGIMS Patna. Seroconversion occur with a mean of 14 days in HCW from the day of diagnosis with past or present infection of COVID-19.


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