• Users Online: 38
  • Print this page
  • Email this page
ORIGINAL ARTICLE
Year : 2021  |  Volume : 7  |  Issue : 1  |  Page : 57-63

Volumetric-modulated arc therapy versus intensity-modulated radiotherapy on the left-sided chest wall and locoregional nodes irradiation in treating postmastectomy breast cancer patients: A comparative dosimetric analysis


1 Department of Medical Physics, State Cancer Institute, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India
2 Department of Radiation Oncology, Paras HMRI Hospital, Patna, Bihar, India
3 Department of Radiotherapy and Radiation Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India

Correspondence Address:
Mukesh Kumar Zope
Department of Medical Physics, State Cancer Institute, Indira Gandhi Institute of Medical Sciences, Patna - 800 014, Bihar
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jigims.jigims_6_21

Rights and Permissions

Purpose: This study was aimed to compare the suitable treatment plan for left-sided chest wall, regional node irradiation by the intensity-modulated radiotherapy (IMRT), and volumetric-modulated arc therapy (VMAT). Materials and Methods: Fifteen patients' computed tomography data set was import into the treatment planning system (Oncentra). Two plans were generated for each patient, the first one using the VMAT technique with two partial arcs and the second one using the IMRT technique with seven coplaner radiation portals using 3D Oncentra TPS with 6 MV photons, step and shoot treatment delivery technique with 80 leaf multileaf collimator, and 1 cm leaf width at the isocenter. The VMAT plans optimized using the collapsed cone (GPU) algorithm and IMRT plans optimized using a collapsed cone algorithm. A hypofractionated prescription dose of 40 Gy/15# was used. The VMAT and IMRT plans compared for Planning Target Volume (PTV) target coverage, homogeneity index (HI), conformity index (CI), and monitor units (MUs) were evaluated. The Organ At Risk (OAR) doses also compared. Results: A comparable PTV coverage (V95%) and mean PTV doses were observed between VMAT and IMRT plans. The PTV maximum dose was higher within IMRT than the VMAT. We observed a better HI for VMAT plans. For conformity index (CI) both plan showed no significant difference. MU values of VMAT are higher than the IMRT treatment in this study. However, VMAT plans show significantly better right lung, heart, and larynx sparing when compared to the IMRT plans. No significant difference was observed in both groups of plan for the right breast and spinal cord. The maximum dose for the left humerus head was compared for both groups of plans. Conclusions: VMAT is dosimetrically superior to the IMRT for irradiation of left-sided chest wall and regional nodes patients in terms of target coverage and OAR sparing.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed240    
    Printed0    
    Emailed0    
    PDF Downloaded29    
    Comments [Add]    

Recommend this journal